Glycerone kinase

From Wikipedia, the free encyclopedia

In enzymology, a glycerone kinase (EC 2.7.1.29) is an enzyme that catalyzes the chemical reaction

ATP + glycerone ADP + glycerone phosphate

Thus, the two substrates of this enzyme are ATP and glycerone, whereas its two products are ADP and glycerone phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:glycerone phosphotransferase. Other names in common use include dihydroxyacetone kinase, acetol kinase, and acetol kinase (phosphorylating). This enzyme participates in glycerolipid metabolism.

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes 1OI2, 1OI3, 1UN8, 1UN9, 1UOD, and 1UOE.

[edit] References

• IUBMB entry for 2.7.1.29
• BRENDA references for 2.7.1.29 (Recommended.)
• PubMed references for 2.7.1.29
• PubMed Central references for 2.7.1.29
• Google Scholar references for 2.7.1.29
• Sellinger OZ and Miller ON (1957). "Phosphorylation of acetol by homogenates of rat liver". Fed. Proc. 16: 245–246. 

[edit] External links

The CAS registry number for this enzyme class is 9027-47-8.

• IUBMB entry for 2.7.1.29

• KEGG entry for 2.7.1.29

• BRENDA entry for 2.7.1.29

• NiceZyme view of 2.7.1.29

• EC2PDB: PDB structures for 2.7.1.29

• PRIAM entry for 2.7.1.29

• PUMA2 entry for 2.7.1.29

• IntEnz: Integrated Enzyme entry for 2.7.1.29

• MetaCyc entry for 2.7.1.29

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0004371: glycerone kinase

• AMIGO entry for GO code 0004371: glycerone kinase