Glycerol-1,2-cyclic-phosphate 2-phosphodiesterase

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In enzymology, a glycerol-1,2-cyclic-phosphate 2-phosphodiesterase (EC 3.1.4.42) is an enzyme that catalyzes the chemical reaction

glycerol 1,2-cyclic phosphate + H₂O glycerol 1-phosphate

Thus, the two substrates of this enzyme are glycerol 1,2-cyclic phosphate and H₂O, whereas its product is glycerol 1-phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is rac-glycerol-1,2-cyclic-phosphate 2-glycerophosphohydrolase. This enzyme is also called rac-glycerol 1:2-cyclic phosphate 2-phosphodiesterase.

[edit] References

• IUBMB entry for 3.1.4.42
• BRENDA references for 3.1.4.42 (Recommended.)
• PubMed references for 3.1.4.42
• PubMed Central references for 3.1.4.42
• Google Scholar references for 3.1.4.42
• Clarke N, Dawson RM (1978). "rac-Glycerol 1:2-cyclic phosphate 2-phosphodiesterase, a new soluble phosphodiesterase of mammalian tissues". Biochem. J. 173: 579–89. PMID 212014. 

[edit] External links

The CAS registry number for this enzyme class is 69458-89-5.

• IUBMB entry for 3.1.4.42

• KEGG entry for 3.1.4.42

• BRENDA entry for 3.1.4.42

• NiceZyme view of 3.1.4.42

• EC2PDB: PDB structures for 3.1.4.42

• PRIAM entry for 3.1.4.42

• PUMA2 entry for 3.1.4.42

• IntEnz: Integrated Enzyme entry for 3.1.4.42

• MetaCyc entry for 3.1.4.42

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047393: glycerol-1,2-cyclic-phosphate 2-phosphodiesterase

• AMIGO entry for GO code 0047393: glycerol-1,2-cyclic-phosphate 2-phosphodiesterase