Glutathione oxidase

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In enzymology, a glutathione oxidase (EC 1.8.3.3) is an enzyme that catalyzes the chemical reaction

2 glutathione + O₂ glutathione disulfide + H₂O₂

Thus, the two substrates of this enzyme are glutathione and O₂, whereas its two products are glutathione disulfide and H₂O₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donors with oxygen as acceptor. The systematic name of this enzyme class is glutathione:oxygen oxidoreductase. This enzyme participates in glutathione metabolism. It employs one cofactor, FAD.

[edit] References

• IUBMB entry for 1.8.3.3
• BRENDA references for 1.8.3.3 (Recommended.)
• PubMed references for 1.8.3.3
• PubMed Central references for 1.8.3.3
• Google Scholar references for 1.8.3.3
• Kusakabe H, Kuninaka A and Yoshino H (1982). "Purification and properties of a new enzyme, glutathione oxidase from Penicillium sp.K-6-5". Agric. Biol. Chem. 46: 2057–2067. 

[edit] External links

The CAS registry number for this enzyme class is 55467-56-6.

• IUBMB entry for 1.8.3.3

• KEGG entry for 1.8.3.3

• BRENDA entry for 1.8.3.3

• NiceZyme view of 1.8.3.3

• EC2PDB: PDB structures for 1.8.3.3

• PRIAM entry for 1.8.3.3

• PUMA2 entry for 1.8.3.3

• IntEnz: Integrated Enzyme entry for 1.8.3.3

• MetaCyc entry for 1.8.3.3

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047950: glutathione oxidase

• AMIGO entry for GO code 0047950: glutathione oxidase