Glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase

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In enzymology, a glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase (EC 3.1.4.51) is an enzyme that catalyzes the chemical reaction

6-(D-glucose-1-phospho)-D-mannosylglycoprotein + H₂O alpha-D-glucose 1-phosphate + D-mannosylglycoprotein

Thus, the two substrates of this enzyme are 6-(D-glucose-1-phospho)-D-mannosylglycoprotein and H₂O, whereas its two products are alpha-D-glucose 1-phosphate and D-mannosylglycoprotein.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is 6-(D-glucose-1-phospho)-D-mannosylglycoprotein glucose-1-phosphohydrolase. This enzyme is also called alpha-glucose-1-phosphate phosphodiesterase.

[edit] References

• IUBMB entry for 3.1.4.51
• BRENDA references for 3.1.4.51 (Recommended.)
• PubMed references for 3.1.4.51
• PubMed Central references for 3.1.4.51
• Google Scholar references for 3.1.4.51
• Srisomsap C, Richardson KL, Jay JC, Marchase RB (1989). "An alpha-glucose-1-phosphate phosphodiesterase is present in rat liver cytosol". J. Biol. Chem. 264: 20540–6. PMID 2555363. 

[edit] External links

The CAS registry number for this enzyme class is 123940-44-3.

• IUBMB entry for 3.1.4.51

• KEGG entry for 3.1.4.51

• BRENDA entry for 3.1.4.51

• NiceZyme view of 3.1.4.51

• EC2PDB: PDB structures for 3.1.4.51

• PRIAM entry for 3.1.4.51

• PUMA2 entry for 3.1.4.51

• IntEnz: Integrated Enzyme entry for 3.1.4.51

• MetaCyc entry for 3.1.4.51

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047399: glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase

• AMIGO entry for GO code 0047399: glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase