GITR

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GITR (glucocorticoid-induced tumor necrosis factor receptor) is a surface receptor molecule that has been shown to be involved in inhibiting the suppressive activity of T-regulatory cells and extending the survival of T-effector cells.[1]

[edit] References

  1. ^ Jun Shimizu, Ph.D (2002). Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance (Web). Tokyo Metropolitan Institute of Gerontology. Retrieved on 2007-11-17.
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