Talk:Gene expression
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Article Grading: The following comments were left by the quality and importance raters: (edit · history · refresh · how to use this template) high school/SAT biology topic; important overview of central MCB topic (most molecular biology research revolves around gene expression in one way or another); changed rating from high to top - tameeria 15:23, 18 February 2007 (UTC) |
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[edit] Measurement
Need slow throughput techniques e.g. northern blot --Zven 12:12, 17 September 2006 (UTC)
I just updated this entire section, adding, for example, the northern blot, and a little more information on DNA microarrays. I also cleaned up the language to make it hopefully more accurate. I also updated the protein-level measurement part, since the original author was apparently unaware that Western blots are still the standard method of choice for reporting protein levels. Let me know what you think. -- Josh 03:36, 7 June 2007 (UTC)
[edit] Is human DNA homo- or hetero- encoding?
Consider the totality of all gene expressions within a chromosome. Are all genes on the same side of the DNA strand? In other words if you split the double helix are all the genes on one strand or are they staggered between the two strands?
- If I remember correctly, which I think I do, each strand is just the mirror image of the other one. Codons on one strand match up with Anti-codons on the other.--Urthogie 21:37, 22 April 2007 (UTC)
- Genes are dispersed among both strands in a single chromosome. With 100% confidence. -- Josh 03:39, 15 May 2007 (UTC)
[edit] Patterns of Gene Expression
moved terms to Glossary of Scientific Terms related to Gene Expression. Removed empty section.
[edit] Housekeeping genes
Why does housekeeping genes redirect to this article? ώЇЌĩ Ѕαи Яоzε †αLҝ 21:50, 11 June 2007 (UTC)
- I'm assuming because there is no 'housekeeping genes' article yet, that you need to underestand gene expression at least a bit to understand housekeeping genes, and that this article is the most informative one that the person making the redirect could find at the time. JetheroTalk 00:25, 9 July 2007 (UTC)
[edit] Intro Sentence
Was:
- '''Gene expression''', or simply '''expression''', is the process by which a [[gene]]'s [[DNA sequence]] is converted into functional [[proteins]].
But:
- DNA is not 'converted', but transcribed, leaving intact DNA behind
- the term 'DNA sequence' does not capture epigenomic 'information', which may indeed be part of the inheritable trait, or genetic information, and have an effect on the amount or structure of the 'expressed' gene or trait.
- not all 'gene expression', and perhaps not even most, results in protein production. Protein is not the only trait, or 'expression' of genetic information
- Sentence from gene article was more comprehensive, but not quite what we need here. "The process of producing a biologically functional molecule of either RNA or protein is called gene expression, and the resulting molecule itself is called a gene product."
- however, this still needs to be simple, so please continue to refine.
So is now:
- '''Gene expression''', or simply '''expression''', is the process by which the inheritable information which comprises a [[gene]], such as the [[DNA sequence]], is made manifest as a physical and biologically functional [[gene product]], such as [[protein]] or [[RNA]].
