User:GAThrawn22/Sandbox/protboxtest2

Insulin
Insulin hexamers
Gene code:	HUGO code:INS
Gene type:	Protein coding
Molecular Weight:	11982 (Da)
Structure:	Solution Structure of Human pro-Insulin Polypeptide
Protein type:	insulin family
Functions:	glucose regulation
Domains:	INS
Motifs:	SP
Diseases:	familial hyperproinsulinemia
Pharmaceuticals:	Humulin, Humalog (Eli Lilly) and Novolin(Novo Nordisk)
Taxa expressing:	Homo sapiens; homologs: many metazoan taxa
Cell types:	pancreas
Subcellular localization:	extracellular
Covalent modifications:	glycation, proteolytic cleavage
Other names:	proinsulin

2-oxoglutarate dehydrogenase E1 component (α-Ketoglutarate dehydrogenase)
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Gene code:	HUGO code:OGDH
Gene type:	protein coding
Molecular Weight:	115942 (Da)
Protein type:	Enzyme: Dehyrogenase
Functions:	converts alpha ketoglutarate to succinyl CoA
Catalytic activity:	2-oxoglutarate + [dihydrolipoyllysine-residue succinyltransferase] lipoyllysine = [dihydrolipoyllysine-residue succinyltransferase] S-succinyldihydrolipoyllysine + CO(2)
Cofactor(s):	Thiamine pyrophosphate
Enzyme Regulation:	Catabolite repressed
Diseases:	Alpha-Ketoglutarate Dehydrogenase Deficiency
Taxa expressing:	Homo sapiens; homologs: ubiquitous among oxidatively respiring organisms
Cell types:	ubiquitous among aerobic cells
Subcellular localization:	mitochondrion
Other names:	Alpha-ketoglutarate dehydrogenase
Pathway(s):	Citric acid cycle, Lysine degradation
Symbol(s):	CF
Entrez:	1431
OMIM:	118950
RefSeq:	NM_004077
UniProt:	O75390
EC number:	4.1.3.7
Locus:	Chr. 12 p11-qter