GARNL1

From Wikipedia, the free encyclopedia

GTPase activating Rap/RanGAP domain-like 1

Identifiers

GARNL1; DKFZp566D133; DKFZp667F074; GRIPE; KIAA0884; TULIP1

External IDs

OMIM: 608884 MGI: 1931050 HomoloGene: 84805

Gene ontology
Molecular Function:	• GTPase activator activity
Cellular Component:	• intracellular • nucleus
Biological Process:	• regulation of small GTPase mediated signal transduction

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_014990 (mRNA)
NP_055805 (protein)

NM_001003719 (mRNA)
NP_001003719 (protein)

Location

Chr 14: 35.08 - 35.35 Mb

Chr 12: 56.52 - 56.74 Mb

Pubmed search

[1]

[2]

GTPase activating Rap/RanGAP domain-like 1, also known as GARNL1, is a human gene.^[1]

[edit] References

^ Entrez Gene: GARNL1 GTPase activating Rap/RanGAP domain-like 1.

[edit] Further reading

Nagase T, Ishikawa K, Suyama M, et al. (1999). "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 5 (6): 355–64. PMID 10048485.
Heng JI, Tan SS (2003). "Cloning and characterization of GRIPE, a novel interacting partner of the transcription factor E12 in developing mouse forebrain.". J. Biol. Chem. 277 (45): 43152–9. doi:10.1074/jbc.M204858200. PMID 12200424.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Swaminathan S, Kiendl F, Körner R, et al. (2004). "RanGAP1*SUMO1 is phosphorylated at the onset of mitosis and remains associated with RanBP2 upon NPC disassembly.". J. Cell Biol. 164 (7): 965–71. doi:10.1083/jcb.200309126. PMID 15037602.
Fortna A, Kim Y, MacLaren E, et al. (2006). "Lineage-specific gene duplication and loss in human and great ape evolution.". PLoS Biol. 2 (7): E207. doi:10.1371/journal.pbio.0020207. PMID 15252450.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Schwarzbraun T, Vincent JB, Schumacher A, et al. (2005). "Cloning, genomic structure, and expression profiles of TULIP1 (GARNL1), a brain-expressed candidate gene for 14q13-linked neurological phenotypes, and its murine homologue.". Genomics 84 (3): 577–86. doi:10.1016/j.ygeno.2004.04.013. PMID 15498464.
Schmid EM, Ford MG, Burtey A, et al. (2007). "Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly.". PLoS Biol. 4 (9): e262. doi:10.1371/journal.pbio.0040262. PMID 16903783.