Fructose-6-phosphate phosphoketolase

From Wikipedia, the free encyclopedia

In enzymology, a fructose-6-phosphate phosphoketolase (EC 4.1.2.22) is an enzyme that catalyzes the chemical reaction

D-fructose 6-phosphate + phosphate acetyl phosphate + D-erythrose 4-phosphate + H₂O

Thus, the two substrates of this enzyme are D-fructose 6-phosphate and phosphate, whereas its 3 products are acetyl phosphate, D-erythrose 4-phosphate, and H₂O.

This enzyme belongs to the family of lyases, specifically the aldehyde-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is D-fructose-6-phosphate D-erythrose-4-phosphate-lyase (adding phosphate; acetyl-phosphate-forming). Other names in common use include D-fructose-6-phosphate D-erythrose-4-phosphate-lyase, and (phosphate-acetylating). This enzyme participates in pentose phosphate pathway.

[edit] References

• IUBMB entry for 4.1.2.22
• BRENDA references for 4.1.2.22 (Recommended.)
• PubMed references for 4.1.2.22
• PubMed Central references for 4.1.2.22
• Google Scholar references for 4.1.2.22
• Schramm M, Klybas V and Racker E (1958). "Phospholytic cleavage of fructose-6-phosphate by fructose-6-phosphate phosphoketolase from Acetobacter xylinum". J. Biol. Chem. 233: 1283–1288. 

[edit] External links

The CAS registry number for this enzyme class is 37290-57-6.

• IUBMB entry for 4.1.2.22

• KEGG entry for 4.1.2.22

• BRENDA entry for 4.1.2.22

• NiceZyme view of 4.1.2.22

• EC2PDB: PDB structures for 4.1.2.22

• PRIAM entry for 4.1.2.22

• PUMA2 entry for 4.1.2.22

• IntEnz: Integrated Enzyme entry for 4.1.2.22

• MetaCyc entry for 4.1.2.22

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047905: fructose-6-phosphate phosphoketolase

• AMIGO entry for GO code 0047905: fructose-6-phosphate phosphoketolase