Formylaspartate deformylase

From Wikipedia, the free encyclopedia

In enzymology, a formylaspartate deformylase (EC 3.5.1.8) is an enzyme that catalyzes the chemical reaction

N-formyl-L-aspartate + H₂O formate + L-aspartate

Thus, the two substrates of this enzyme are N-formyl-L-aspartate and H₂O, whereas its two products are formate and L-aspartate.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-formyl-L-aspartate amidohydrolase. This enzyme is also called formylaspartic formylase (formylase I, formylase II). This enzyme participates in histidine metabolism and glyoxylate and dicarboxylate metabolism.

[edit] References

• IUBMB entry for 3.5.1.8
• BRENDA references for 3.5.1.8 (Recommended.)
• PubMed references for 3.5.1.8
• PubMed Central references for 3.5.1.8
• Google Scholar references for 3.5.1.8
• Ohmura E and Hayaishi O (1957). "Enzymatic conversion of formylaspartic acid to aspartic acid". J. Biol. Chem. 227: 181–190. 

[edit] External links

The CAS registry number for this enzyme class is 9025-09-6.

• IUBMB entry for 3.5.1.8

• KEGG entry for 3.5.1.8

• BRENDA entry for 3.5.1.8

• NiceZyme view of 3.5.1.8

• EC2PDB: PDB structures for 3.5.1.8

• PRIAM entry for 3.5.1.8

• PUMA2 entry for 3.5.1.8

• IntEnz: Integrated Enzyme entry for 3.5.1.8

• MetaCyc entry for 3.5.1.8

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047902: formylaspartate deformylase

• AMIGO entry for GO code 0047902: formylaspartate deformylase