Formyl-CoA transferase

From Wikipedia, the free encyclopedia

In enzymology, a formyl-CoA transferase (EC 2.8.3.16) is an enzyme that catalyzes the chemical reaction

formyl-CoA + oxalate formate + oxalyl-CoA

Thus, the two substrates of this enzyme are formyl-CoA and oxalate, whereas its two products are formate and oxalyl-CoA.

This enzyme belongs to the family of transferases, specifically the CoA-transferases. The systematic name of this enzyme class is formyl-CoA:oxalate CoA-transferase. Other names in common use include formyl-coenzyme A transferase, and formyl-CoA oxalate CoA-transferase.

[edit] Structural studies

As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes 1T3Z, 1T4C, 1VGQ, and 1VGR.

[edit] References

• IUBMB entry for 2.8.3.16
• BRENDA references for 2.8.3.16 (Recommended.)
• PubMed references for 2.8.3.16
• PubMed Central references for 2.8.3.16
• Google Scholar references for 2.8.3.16
• Baetz AL, Allison MJ (1990). "Purification and characterization of formyl-coenzyme A transferase from Oxalobacter formigenes". J. Bacteriol. 172: 3537–40. PMID 2361939. 
• Sidhu H, Ogden SD, Lung HY, Luttge BG, Baetz AL, Peck AB (1997). "DNA sequencing and expression of the formyl coenzyme A transferase gene, frc, from Oxalobacter formigenes". J. Bacteriol. 179: 3378–81. PMID 9150242. 

[edit] External links

The CAS registry number for this enzyme class is 128826-27-7.

• IUBMB entry for 2.8.3.16

• KEGG entry for 2.8.3.16

• BRENDA entry for 2.8.3.16

• NiceZyme view of 2.8.3.16

• EC2PDB: PDB structures for 2.8.3.16

• PRIAM entry for 2.8.3.16

• PUMA2 entry for 2.8.3.16

• IntEnz: Integrated Enzyme entry for 2.8.3.16

• MetaCyc entry for 2.8.3.16

• Atomic-resolution structures of enzymes belonging to this class