Formate kinase

From Wikipedia, the free encyclopedia

In enzymology, a formate kinase (EC 2.7.2.6) is an enzyme that catalyzes the chemical reaction

ATP + formate ADP + formyl phosphate

Thus, the two substrates of this enzyme are ATP and formate, whereas its two products are ADP and formyl phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with a carboxy group as acceptor. The systematic name of this enzyme class is ATP:formate phosphotransferase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

[edit] References

• IUBMB entry for 2.7.2.6
• BRENDA references for 2.7.2.6 (Recommended.)
• PubMed references for 2.7.2.6
• PubMed Central references for 2.7.2.6
• Google Scholar references for 2.7.2.6
• Sly WS and Stadtman ER (1963). "Formate metabolism. II. Enzymatic synthesis of formyl phosphate and formyl coenzyme A in Clostridium cylindrosporum". J. Biol. Chem. 238: 2639–2647. 

[edit] External links

The CAS registry number for this enzyme class is 9026-65-7.

• IUBMB entry for 2.7.2.6

• KEGG entry for 2.7.2.6

• BRENDA entry for 2.7.2.6

• NiceZyme view of 2.7.2.6

• EC2PDB: PDB structures for 2.7.2.6

• PRIAM entry for 2.7.2.6

• PUMA2 entry for 2.7.2.6

• IntEnz: Integrated Enzyme entry for 2.7.2.6

• MetaCyc entry for 2.7.2.6

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047900: formate kinase

• AMIGO entry for GO code 0047900: formate kinase