FMNL2

From Wikipedia, the free encyclopedia

Formin-like 2

Identifiers

FMNL2; FHOD2; FLJ37546

External IDs

MGI: 1918659 HomoloGene: 70871

Gene ontology
Molecular Function:	• transcription factor activity • actin binding
Cellular Component:	• nucleus
Biological Process:	• regulation of transcription, DNA-dependent • cellular component organization and biogenesis • actin cytoskeleton organization and biogenesis

Orthologs

Human

Mouse

Refseq

NM_052905 (mRNA)
NP_443137 (protein)

XM_901882 (mRNA)
XP_906975 (protein)

Location

Chr 2: 152.9 - 153.21 Mb

Chr 2: 52.93 - 52.96 Mb

Pubmed search

[1]

[2]

Formin-like 2, also known as FMNL2, is a human gene.^[1]

This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has yet to be determined.^[1]

[edit] References

^ ^a ^b Entrez Gene: FMNL2 formin-like 2.

[edit] Further reading

Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Colland F, Jacq X, Trouplin V, et al. (2004). "Functional proteomics mapping of a human signaling pathway.". Genome Res. 14 (7): 1324–32. doi:10.1101/gr.2334104. PMID 15231748.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Katoh M, Katoh M (2003). "Identification and characterization of human FMNL1, FMNL2 and FMNL3 genes in silico.". Int. J. Oncol. 22 (5): 1161–8. PMID 12684686.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Nagase T, Kikuno R, Ohara O (2002). "Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins.". DNA Res. 8 (4): 179–87. PMID 11572484.
Dias Neto E, Correa RG, Verjovski-Almeida S, et al. (2000). "Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.". Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491–6. PMID 10737800.
Adams MD, Dubnick M, Kerlavage AR, et al. (1992). "Sequence identification of 2,375 human brain genes.". Nature 355 (6361): 632–4. doi:10.1038/355632a0. PMID 1538749.