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| FinP |
 |
| Type: |
Gene; |
| 2° structure: |
Published; PubMed |
| Seed alignment: |
Griffiths-Jones SR |
| Avg length: |
77.6 nucleotides |
| Avg identity: |
91% |
|
FinP encodes an antisense non-coding RNA gene that is complementary to part of the 5' UTR of the traJ mRNA. The FinOP system regulates the transfer of F-like plasmids. The traJ gene encodes a protein required for transcription from the major transfer promoter, pY. The FinO protein is essential for effective repression, acting by binding to FinP and protecting it from RNase E degradation.
[edit] References
- [1] Jerome, LJ; van Biesen T, Frost LS (1999). "Degradation of FinP antisense RNA from F-like plasmids: the RNA-binding protein, FinO, protects FinP from ribonuclease E". J Mol Biol 285: 1457–1473. doi:10.1006/jmbi.1998.2404. PMID 9917389.
- [2] Arthur, DC; Ghetu AF, Gubbins MJ, Edwards RA, Frost LS, Glover JN (2003). "FinO is an RNA chaperone that facilitates sense-antisense RNA interactions". EMBO J 22: 6346–6355. doi:10.1093/emboj/cdg607. PMID 14633993.
[edit] External links
