Fibrinoid necrosis

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Fibrinoid necrosis is a type of necrosis that can be seen in blood vessel walls. It is associated with immune-complex vasculitis and hypertenstion. Immune complexes, complement and plasma proteins deposit in damaged vessel walls, giving the tissue a smudgy, bright pink appearance on histological examination.[1]

Fibrinoid necrosis is a histopathological hallmark of malignant hypertension (blood pressure greater than 200/130 mmHg).[2]

[edit] References

  1. ^ Kumar, V., Abbas, A.K., and Fausto, N. "Robbins and Cotran Pathologic Basis of Disease" (2005). 7th ed. p. 214.
  2. ^ Kumar, V. et al. Ibid., at p. 1007.