Extraglomerular mesangial cell

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Extraglomerular mesangial cells (or lacis cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.

Lacis cells form the juxtaglomerular apparatus in combination with two other types of cells: the macula densa of the distal convoluted tubule and Juxtaglomerular cells of the afferent arteriole. This apparatus controls blood pressure through the Renin-Angiotensin-Aldosterone system. The specific function of Lacis cells is not well understood, although it has been associated with the secretion of erythropoietin. ^[1]

[edit] See also

• mesangium
• intraglomerular mesangial cells

[edit] External links

• UIUC Histology Subject 1010
• m_10/12526143 at Dorland's Medical Dictionary

[edit] References

1. ^ Junqueira, Luiz C.; Jose Carneiro (2003). Basic Histology. McGraw-Hill. ISBN 0838505902. 

v • d • e Urinary system – Kidney Layers Renal fascia • Renal capsule • Renal cortex  (Renal column) • Renal medulla (Renal sinus, Renal pyramids, medullary interstitium) • Renal lobe • Cortical lobule • Medullary ray • Nephron Afferent circulation Renal artery → Segmental arteries → Interlobar arteries → Arcuate arteries → Cortical radial arteries → Afferent arterioles → Renal corpuscle (Glomerulus, Bowman's capsule) Renal tubule Proximal tubule → Loop of Henle (Descending, Thin ascending, Thick ascending) → Distal convoluted tubule → Connecting tubule → Collecting ducts → Duct of Bellini → Renal papilla → Minor calyx → Major calyx → Renal pelvis → Ureter Efferent circulation Glomerulus → Efferent arterioles → Peritubular capillaries / Vasa recta → Arcuate vein → Interlobar veins → Renal vein Juxtaglomerular apparatus Macula densa • Juxtaglomerular cells • Extraglomerular mesangial cell Filtration Glomerular basement membrane • Podocyte • Filtration slits • Intraglomerular mesangial cell • Tubular fluid Renal physiology Acid base physiology • Fluid balance