Evodiamine

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Evodiamine
Systematic (IUPAC) name
Evodiamine
Identifiers
CAS number	518-17-2
ATC code	?
PubChem	151289
Chemical data
Formula	C19H17N3O
Mol. mass	303.358 g/mol
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

Evodiamine is a chemical which is extracted from the Evodia spp family of plants which has been shown to reduce fat uptake in mouse studies.^{[citation needed]} Its method is believed to be similar to capsaicin, but retains none of the "hot" taste.^{[citation needed]}

Evodiamine may interact with UCP1, which is a thermogenic protein that allows energy to be burned as heat.

[edit] References

• Capsaicin-like anti-obese activities of evodiamine from fruits of Evodia rutaecarpa, a vanilloid receptor agonist.

[[Evodiamine improves diet-induced obesity in a UCP1-independent manner: Involvement of anti-adipogenic mechanism and ERK/MAPK signaling. Wang T, Wang Y, Kontani Y, Kobayashi Y, Sato Y, Mori N, Yamashita H. Endocrinology. 2007 Sep 20; [Epub ahead of print]]http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=17884939&ordinalpos=7&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum]