EVI5

From Wikipedia, the free encyclopedia

Ecotropic viral integration site 5

Identifiers

EVI5; NB4S

External IDs

OMIM: 602942 MGI: 104736 HomoloGene: 88726

Gene ontology
Molecular Function:	• protein binding
Cellular Component:	• nucleus
Biological Process:	• cell cycle • multicellular organismal development • cell proliferation • cell division

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_005665 (mRNA)
NP_005656 (protein)

NM_007964 (mRNA)
NP_031990 (protein)

Location

Chr 1: 92.75 - 93.03 Mb

Chr 5: 107.99 - 108.12 Mb

Pubmed search

[1]

[2]

Ecotropic viral integration site 5, also known as EVI5, is a human gene.^[1]

[edit] References

^ Entrez Gene: EVI5 ecotropic viral integration site 5.

[edit] Further reading

Westlake CJ, Junutula JR, Simon GC, et al. (2007). "Identification of Rab11 as a small GTPase binding protein for the Evi5 oncogene.". Proc. Natl. Acad. Sci. U.S.A. 104 (4): 1236-41. doi:10.1073/pnas.0610500104. PMID 17229837.
Faitar SL, Sossey-Alaoui K, Ranalli TA, Cowell JK (2006). "EVI5 protein associates with the INCENP-aurora B kinase-survivin chromosomal passenger complex and is involved in the completion of cytokinesis.". Exp. Cell Res. 312 (12): 2325-35. doi:10.1016/j.yexcr.2006.03.032. PMID 16764853.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315-21. doi:10.1038/nature04727. PMID 16710414.
Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle.". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391-6. doi:10.1073/pnas.0507066103. PMID 16565220.
Eldridge AG, Loktev AV, Hansen DV, et al. (2006). "The evi5 oncogene regulates cyclin accumulation by stabilizing the anaphase-promoting complex inhibitor emi1.". Cell 124 (2): 367-80. doi:10.1016/j.cell.2005.10.038. PMID 16439210.
Faitar SL, Dabbeekeh JT, Ranalli TA, Cowell JK (2005). "EVI5 is a novel centrosomal protein that binds to alpha- and gamma-tubulin.". Genomics 86 (5): 594-605. doi:10.1016/j.ygeno.2005.06.002. PMID 16033705.
Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.". Nat. Biotechnol. 22 (6): 707-16. doi:10.1038/nbt971. PMID 15146197.
Roberts T, Chernova O, Cowell JK (1999). "NB4S, a member of the TBC1 domain family of genes, is truncated as a result of a constitutional t(1;10)(p22;q21) chromosome translocation in a patient with stage 4S neuroblastoma.". Hum. Mol. Genet. 7 (7): 1169-78. PMID 9618176.