Erythritol kinase

From Wikipedia, the free encyclopedia

In enzymology, an erythritol kinase (EC 2.7.1.27) is an enzyme that catalyzes the chemical reaction

ATP + erythritol ADP + D-erythritol 4-phosphate

Thus, the two substrates of this enzyme are ATP and erythritol, whereas its two products are ADP and D-erythritol 4-phosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:erythritol 4-phosphotransferase. This enzyme is also called erythritol kinase (phosphorylating).

Contents 1 Structural studies 2 References 3 External links 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1V5S.

[edit] References

• IUBMB entry for 2.7.1.27
• BRENDA references for 2.7.1.27 (Recommended.)
• PubMed references for 2.7.1.27
• PubMed Central references for 2.7.1.27
• Google Scholar references for 2.7.1.27
• HOLTEN D, FROMM HJ (1961). "Purification and properties of erythritol kinase from Propionibacterium pentosaceum". J. Biol. Chem. 236: 2581–4. PMID 13908588. 
• HOLTEN D, FROMM HJ (1961). "Purification and properties of erythritol kinase from Propionibacterium pentosaceum". J. Biol. Chem. 236: 2581–4. PMID 13908588. 

[edit] External links

The CAS registry number for this enzyme class is 9030-64-2.

• IUBMB entry for 2.7.1.27

• KEGG entry for 2.7.1.27

• BRENDA entry for 2.7.1.27

• NiceZyme view of 2.7.1.27

• EC2PDB: PDB structures for 2.7.1.27

• PRIAM entry for 2.7.1.27

• PUMA2 entry for 2.7.1.27

• IntEnz: Integrated Enzyme entry for 2.7.1.27

• MetaCyc entry for 2.7.1.27

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047878: erythritol kinase

• AMIGO entry for GO code 0047878: erythritol kinase