Ergonovine

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Ergonovine
Systematic (IUPAC) name
?
Identifiers
CAS number	478-94-4
ATC code	?
PubChem	?
Chemical data
Formula	C19H23N3O2
Mol. mass	325.41 g/mol
Synonyms	Ergonovine, Lysergic acid beta-propanolamide
Pharmacokinetic data
Bioavailability	?
Metabolism	hepatic
Half life	?
Excretion	renal
Therapeutic considerations
Pregnancy cat.	?
Legal status	?(US)
Routes	Oral

Ergonovine, also known as ergometrine or d-lysergic acid beta-propanolamide, is an ergoline (and lysergamide) derivative, and one of the primary ergot and morning glory alkaloids . It is chemically similar to LSD, ergine, and lysergic acid.

Contents 1 Medical use 2 Recreational use 3 Legal status 4 References

[edit] Medical use

It has a medical use in obstetrics to facilitate delivery of the placenta and to prevent bleeding after childbirth by causing smooth muscle tissue in the blood vessel walls to narrow, thereby reducing blood flow. It is usually combined with oxytocin (syntocinon) as syntometrine.

[edit] Recreational use

According to TIHKAL by Alexander Shulgin, ergonovine has LSD-like action at levels of 2-10 milligrams. Clinical dosages are about ten times lower.

[edit] Legal status

Ergometrine is listed as Table I precursors under the United Nations Convention Against Illicit Traffic in Narcotic Drugs and Psychotropic Substances, due to its structural similarity to LSD.^[1]

v • d • e Ergolines Lysergic acid derivatives Bromocriptine, Cabergoline, Ergine, Ergonovine, Ergotamine, Lysergic acid, Lysergol, LSD, D-Lysergic acid hydroxyethylamide, Lisuride, Methergine, Methysergide, Pergolide Hallucinogenic lysergamides AL-LAD, ALD-52, BU-LAD, CYP-LAD, DAL, DAM-57, Ergonovine, ETH-LAD, LAE-32, LSD, LPD-824, LSM-775, D-Lysergic acid N-(α-hydroxyethyl)amide, Methylergonovine, MLD-41, PARGY-LAD, PRO-LAD Other ergolines Ergoline Natural sources Argyreia nervosa, Claviceps spp., Ipomoea tricolor, Ipomoea violacea, Rivea corymbosa

[edit] References