EPS8L3

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EPS8-like 3
PDB rendering based on 1wxt.
Available structures: 1wxt
Identifiers
Symbol(s) EPS8L3; EPS8R3; FLJ21522; MGC16817
External IDs MGI: 2139743 HomoloGene: 15878
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 79574 99662
Ensembl ENSG00000198758 ENSMUSG00000040600
Uniprot Q8TE67 Q91WL0
Refseq NM_024526 (mRNA)
NP_078802 (protein)		 NM_133867 (mRNA)
NP_598628 (protein)
Location Chr 1: 110.09 - 110.11 Mb Chr 3: 108.01 - 108.02 Mb
Pubmed search [1] [2]

EPS8-like 3, also known as EPS8L3, is a human gene.[1]

This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. Alternatively spliced transcript variants encoding different isoforms exist.[1]

[edit] References

  1. ^ a b Entrez Gene: EPS8L3 EPS8-like 3.

[edit] Further reading

  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315-21. doi:10.1038/nature04727. PMID 16710414. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Offenhäuser N, Borgonovo A, Disanza A, et al. (2004). "The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathway.". Mol. Biol. Cell 15 (1): 91-8. doi:10.1091/mbc.E03-06-0427. PMID 14565974. 
  • Tocchetti A, Confalonieri S, Scita G, et al. (2003). "In silico analysis of the EPS8 gene family: genomic organization, expression profile, and protein structure.". Genomics 81 (2): 234-44. PMID 12620401. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149-56. PMID 9373149. 
  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171-4. PMID 8125298. 
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