EPS15L1

From Wikipedia, the free encyclopedia

Epidermal growth factor receptor pathway substrate 15-like 1

Identifiers

External IDs

Gene ontology
Molecular Function:	• calcium ion binding • protein binding
Cellular Component:	• nucleus • coated pit
Biological Process:	• endocytosis

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_021235 (mRNA)
NP_067058 (protein)

NM_007944 (mRNA)
NP_031970 (protein)

Location

Chr 19: 16.33 - 16.44 Mb

Chr 8: 75.27 - 75.33 Mb

Pubmed search

[1]

[2]

Epidermal growth factor receptor pathway substrate 15-like 1, also known as EPS15L1, is a human gene.^[1]

[edit] References

^ Entrez Gene: EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1.

[edit] Further reading

Salcini AE, Confalonieri S, Doria M, et al. (1997). "Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module.". Genes Dev. 11 (17): 2239–49. PMID 9303539.
Carbone R, Fré S, Iannolo G, et al. (1998). "eps15 and eps15R are essential components of the endocytic pathway.". Cancer Res. 57 (24): 5498–504. PMID 9407958.
Coda L, Salcini AE, Confalonieri S, et al. (1998). "Eps15R is a tyrosine kinase substrate with characteristics of a docking protein possibly involved in coated pits-mediated internalization.". J. Biol. Chem. 273 (5): 3003–12. PMID 9446614.
Chen H, Fre S, Slepnev VI, et al. (1998). "Epsin is an EH-domain-binding protein implicated in clathrin-mediated endocytosis.". Nature 394 (6695): 793–7. doi:10.1038/29555. PMID 9723620.
Ueki N, Oda T, Kondo M, et al. (1999). "Selection system for genes encoding nuclear-targeted proteins.". Nat. Biotechnol. 16 (13): 1338–42. doi:10.1038/4315. PMID 9853615.
Doria M, Salcini AE, Colombo E, et al. (2000). "The eps15 homology (EH) domain-based interaction between eps15 and hrb connects the molecular machinery of endocytosis to that of nucleocytosolic transport.". J. Cell Biol. 147 (7): 1379–84. PMID 10613896.
Offenhäuser N, Santolini E, Simeone A, Di Fiore PP (2000). "Differential patterns of expression of Eps15 and Eps15R during mouse embryogenesis.". Mech. Dev. 95 (1-2): 309–12. PMID 10906484.
Martina JA, Bonangelino CJ, Aguilar RC, Bonifacino JS (2001). "Stonin 2: an adaptor-like protein that interacts with components of the endocytic machinery.". J. Cell Biol. 153 (5): 1111–20. PMID 11381094.
Poupon V, Polo S, Vecchi M, et al. (2002). "Differential nucleocytoplasmic trafficking between the related endocytic proteins Eps15 and Eps15R.". J. Biol. Chem. 277 (11): 8941–8. doi:10.1074/jbc.M108385200. PMID 11777906.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.". Anal. Chem. 76 (10): 2763–72. doi:10.1021/ac035352d. PMID 15144186.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.
Schmid EM, Ford MG, Burtey A, et al. (2007). "Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly.". PLoS Biol. 4 (9): e262. doi:10.1371/journal.pbio.0040262. PMID 16903783.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.