Entactin

From Wikipedia, the free encyclopedia

Nidogen 1

PDB rendering based on 1gl4.

Available structures: 1gl4, 1h4u

Identifiers

Symbol(s)

NID1; NID

External IDs

OMIM: 131390 MGI: 97342 HomoloGene: 1878

Gene ontology
Molecular Function:	• extracellular matrix structural constituent • calcium ion binding • protein binding
Cellular Component:	• basement membrane • membrane
Biological Process:	• cell adhesion • cell-matrix adhesion • bioluminescence • protein-chromophore linkage

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_002508 (mRNA)
NP_002499 (protein)

NM_010917 (mRNA)
NP_035047 (protein)

Location

Chr 1: 234.21 - 234.3 Mb

n/a

Pubmed search

[1]

[2]

Entactin (or nidogen) is a component of the basement membrane alongside other components such as collagen type IV, proteoglycans ( heparan sulfate and glycosaminoglycans), laminin and fibronectin.

This gene encodes a member of the nidogen family of basement membrane glycoproteins. The protein interacts with several other components of basement membranes, and may play a role in cell interactions with the extracellular matrix.^[1]

[edit] References

^ Entrez Gene: NID1 nidogen 1.

[edit] Further reading

Chung AE, Durkin ME (1990). "Entactin: structure and function.". Am. J. Respir. Cell Mol. Biol. 3 (4): 275–82. PMID 2119632.
Yurchenco PD, Schittny JC (1990). "Molecular architecture of basement membranes.". FASEB J. 4 (6): 1577–90. PMID 2180767.