EMX1

From Wikipedia, the free encyclopedia

Empty spiracles homeobox 1

Identifiers

External IDs

OMIM: 600034 MGI: 95387 HomoloGene: 55799

Gene ontology
Molecular Function:	• transcription factor activity • sequence-specific DNA binding
Cellular Component:	• nucleus
Biological Process:	• regulation of transcription, DNA-dependent • multicellular organismal development • brain development • neuron differentiation

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_001040404 (mRNA)
NP_001035494 (protein)

NM_010131 (mRNA)
NP_034261 (protein)

Location

Chr 2: 73 - 73.01 Mb

Chr 6: 85.15 - 85.17 Mb

Pubmed search

[1]

[2]

Empty spiracles homeobox 1, also known as EMX1, is a human gene.^[1]

[edit] References

^ Entrez Gene: EMX1 empty spiracles homeobox 1.

[edit] Further reading

Simeone A, Gulisano M, Acampora D, et al. (1992). "Two vertebrate homeobox genes related to the Drosophila empty spiracles gene are expressed in the embryonic cerebral cortex.". EMBO J. 11 (7): 2541–50. PMID 1352754.
Solaro P, Greger B, Kemper B (1995). "Detection and partial purification of a cruciform-resolving activity (X-solvase) from nuclear extracts of mouse B-cells.". Eur. J. Biochem. 230 (3): 926–933. PMID 7601155.
Kastury K, Druck T, Huebner K, et al. (1994). "Chromosome locations of human EMX and OTX genes.". Genomics 22 (1): 41–5. doi:10.1006/geno.1994.1343. PMID 7959790.
Briata P, Di Blas E, Gulisano M, et al. (1997). "EMX1 homeoprotein is expressed in cell nuclei of the developing cerebral cortex and in the axons of the olfactory sensory neurons.". Mech. Dev. 57 (2): 169–80. PMID 8843394.
Santi E, Capone S, Mennuni C, et al. (2000). "Bacteriophage lambda display of complex cDNA libraries: a new approach to functional genomics.". J. Mol. Biol. 296 (2): 497–508. doi:10.1006/jmbi.1999.3471. PMID 10669604.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4.". Nature 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.