EMILIN1

From Wikipedia, the free encyclopedia

Elastin microfibril interfacer 1

Identifiers

EMILIN1; DKFZP586M121; EMILIN; EMILIN-1; gp115

External IDs

OMIM: 130660 MGI: 1926189 HomoloGene: 5117

Gene ontology
Molecular Function:	• extracellular matrix constituent conferring elasticity • identical protein binding
Cellular Component:	• proteinaceous extracellular matrix • cytoplasm
Biological Process:	• phosphate transport • cell adhesion

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_007046 (mRNA)
NP_008977 (protein)

NM_133918 (mRNA)
NP_598679 (protein)

Location

Chr 2: 27.15 - 27.16 Mb

Chr 5: 31.19 - 31.2 Mb

Pubmed search

[1]

[2]

Elastin microfibril interfacer 1, also known as EMILIN1, is a human gene.^[1]

[edit] References

^ Entrez Gene: EMILIN1 elastin microfibril interfacer 1.

[edit] Further reading

Doliana R, Mongiat M, Bucciotti F, et al. (1999). "EMILIN, a component of the elastic fiber and a new member of the C1q/tumor necrosis factor superfamily of proteins.". J. Biol. Chem. 274 (24): 16773–81. PMID 10358019.
Doliana R, Canton A, Bucciotti F, et al. (2000). "Structure, chromosomal localization, and promoter analysis of the human elastin microfibril interfase located proteIN (EMILIN) gene.". J. Biol. Chem. 275 (2): 785–92. PMID 10625608.
Mongiat M, Mungiguerra G, Bot S, et al. (2000). "Self-assembly and supramolecular organization of EMILIN.". J. Biol. Chem. 275 (33): 25471–80. doi:10.1074/jbc.M001426200. PMID 10821830.
Sterzel RB, Hartner A, Schlötzer-Schrehardt U, et al. (2000). "Elastic fiber proteins in the glomerular mesangium in vivo and in cell culture.". Kidney Int. 58 (4): 1588–602. doi:10.1046/j.1523-1755.2000.00320.x. PMID 11012893.
Doliana R, Bot S, Mungiguerra G, et al. (2001). "Isolation and characterization of EMILIN-2, a new component of the growing EMILINs family and a member of the EMI domain-containing superfamily.". J. Biol. Chem. 276 (15): 12003–11. doi:10.1074/jbc.M011591200. PMID 11278945.
Spessotto P, Cervi M, Mucignat MT, et al. (2003). "beta 1 Integrin-dependent cell adhesion to EMILIN-1 is mediated by the gC1q domain.". J. Biol. Chem. 278 (8): 6160–7. doi:10.1074/jbc.M208322200. PMID 12456677.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Verdone G, Colebrooke SA, Boyd J, et al. (2004). "Sequence-specific backbone NMR assignments for the C-terminal globular domain of EMILIN-1.". J. Biomol. NMR 29 (1): 91–2. doi:10.1023/B:JNMR.0000019460.94913.6a. PMID 15017143.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Wang L, Zhu YF, Guo XJ, et al. (2006). "A two-dimensional electrophoresis reference map of human ovary.". J. Mol. Med. 83 (10): 812–21. doi:10.1007/s00109-005-0676-y. PMID 16021519.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Lewandrowski U, Moebius J, Walter U, Sickmann A (2006). "Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach.". Mol. Cell Proteomics 5 (2): 226–33. doi:10.1074/mcp.M500324-MCP200. PMID 16263699.
Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.