EIF3G

From Wikipedia, the free encyclopedia

Eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa

PDB rendering based on 2cq0.

Available structures: 2cq0

Identifiers

Symbol(s)

EIF3S4; EIF3-P42; eIF3-delta; eIF3-p44; eIF3g

External IDs

OMIM: 603913 MGI: 1858258 HomoloGene: 2784

Gene ontology
Molecular Function:	• nucleotide binding • RNA binding • translation initiation factor activity • protein binding
Biological Process:	• translation • regulation of translational initiation

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_003755 (mRNA)
NP_003746 (protein)

NM_016876 (mRNA)
NP_058572 (protein)

Location

Chr 19: 10.09 - 10.09 Mb

Chr 9: 20.65 - 20.65 Mb

Pubmed search

[1]

[2]

Eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa, also known as EIF3S4, is a human gene.^[1]

[edit] References

^ Entrez Gene: EIF3S4 eukaryotic translation initiation factor 3, subunit 4 delta, 44kDa.

[edit] Further reading

Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags.". Genome Res. 6 (9): 807-28. PMID 8889549.
Asano K, Kinzy TG, Merrick WC, Hershey JW (1997). "Conservation and diversity of eukaryotic translation initiation factor eIF3.". J. Biol. Chem. 272 (2): 1101-9. PMID 8995409.
Méthot N, Rom E, Olsen H, Sonenberg N (1997). "The human homologue of the yeast Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170.". J. Biol. Chem. 272 (2): 1110-6. PMID 8995410.
Block KL, Vornlocher HP, Hershey JW (1998). "Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3.". J. Biol. Chem. 273 (48): 31901-8. PMID 9822659.
Bandyopadhyay A, Maitra U (1999). "Cloning and characterization of the p42 subunit of mammalian translation initiation factor 3 (eIF3): demonstration that eIF3 interacts with eIF5 in mammalian cells.". Nucleic Acids Res. 27 (5): 1331-7. PMID 9973622.
Hou CL, Tang C, Roffler SR, Tang TK (2000). "Protein 4.1R binding to eIF3-p44 suggests an interaction between the cytoskeletal network and the translation apparatus.". Blood 96 (2): 747-53. PMID 10887144.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Mayeur GL, Fraser CS, Peiretti F, et al. (2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3.". Eur. J. Biochem. 270 (20): 4133-9. PMID 14519125.
Fraser CS, Lee JY, Mayeur GL, et al. (2004). "The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro.". J. Biol. Chem. 279 (10): 8946-56. doi:10.1074/jbc.M312745200. PMID 14688252.
Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation.". Genome Res. 14 (7): 1315-23. doi:10.1101/gr.2122004. PMID 15231747.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins.". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130-5. doi:10.1073/pnas.0404720101. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.
Ogawa F, Kasai M, Akiyama T (2006). "A functional link between Disrupted-In-Schizophrenia 1 and the eukaryotic translation initiation factor 3.". Biochem. Biophys. Res. Commun. 338 (2): 771-6. doi:10.1016/j.bbrc.2005.10.013. PMID 16243297.
Kim JT, Kim KD, Song EY, et al. (2007). "Apoptosis-inducing factor (AIF) inhibits protein synthesis by interacting with the eukaryotic translation initiation factor 3 subunit p44 (eIF3g).". FEBS Lett. 580 (27): 6375-83. doi:10.1016/j.febslet.2006.10.049. PMID 17094969.
Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.