Effective renal plasma flow

Effective renal plasma flow (eRPF) is a measure used in renal physiology to calculate renal plasma flow (RPF) and hence estimate renal function.

$eRPF = RPF \times extraction ratio$ ^[1]

Where extraction ratio is the amount of compound entering the kidney that got excreted into the final urine. ^[2]

When using a compound with an extraction ratio near 1, such as para-aminohippurate (PAH), then eRPF is almost equal to RPF. Therefore, PAH clearance is a method to estimate renal plasma flow.

[edit] References

v • d • e Urinary system, physiology: renal physiology and acid base physiology

Filtration	Renal blood flow - Ultrafiltration - Countercurrent exchange

Hormones affecting filtration	Antidiuretic hormone (ADH) - Aldosterone - Atrial natriuretic peptide

Secretion/clearance	Pharmacokinetics - Clearance of medications

Reabsorption	Solvent drag -Na⁺ - Cl^- -urea -glucose -oligopeptides -protein

Endocrine	Renin - Erythropoietin (EPO) - Calcitriol (Active vitamin D) - Prostaglandins

Assessing Renal function / Measures of dialysis	Glomerular filtration rate - Creatinine clearance - Renal clearance ratio - Urea reduction ratio - Kt/V - Standardized Kt/V - Hemodialysis product - PAH clearance (Effective renal plasma flow - Extraction ratio)

Acid base physiology	Fluid balance - Darrow Yannet diagram - Body water - Interstitial fluid - Extracellular fluid - Intracellular fluid/Cytosol - Plasma - Transcellular fluid - Base excess - Davenport diagram - Anion gap - Arterial blood gas

Buffering/compensation	Bicarbonate buffering system - Respiratory compensation - Renal compensation