EEF1E1

From Wikipedia, the free encyclopedia

Eukaryotic translation elongation factor 1 epsilon 1

Identifiers

EEF1E1; P18; AIMP3

External IDs

OMIM: 609206 MGI: 1913393 HomoloGene: 3161

Gene ontology
Molecular Function:	• protein binding
Cellular Component:	• nucleus • cytoplasm • aminoacyl-tRNA synthetase multienzyme complex
Biological Process:	• regulation of progression through cell cycle • DNA repair • translation • negative regulation of cell proliferation • embryonic development • positive regulation of apoptosis • positive regulation of DNA damage response, signal transduction by p53 class mediator

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_004280 (mRNA)
NP_004271 (protein)

NM_025380 (mRNA)
NP_079656 (protein)

Location

Chr 6: 8.02 - 8.05 Mb

Chr 13: 38.65 - 38.67 Mb

Pubmed search

[1]

[2]

Eukaryotic translation elongation factor 1 epsilon 1, also known as EEF1E1, is a human gene.^[1]

[edit] References

^ Entrez Gene: EEF1E1 eukaryotic translation elongation factor 1 epsilon 1.

[edit] Further reading

Norcum MT (1991). "Structural analysis of the high molecular mass aminoacyl-tRNA synthetase complex. Effects of neutral salts and detergents.". J. Biol. Chem. 266 (23): 15398-405. PMID 1651330.
Mao M, Fu G, Wu JS, et al. (1998). "Identification of genes expressed in human CD34(+) hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning.". Proc. Natl. Acad. Sci. U.S.A. 95 (14): 8175-80. PMID 9653160.
Quevillon S, Robinson JC, Berthonneau E, et al. (1999). "Macromolecular assemblage of aminoacyl-tRNA synthetases: identification of protein-protein interactions and characterization of a core protein.". J. Mol. Biol. 285 (1): 183-95. doi:10.1006/jmbi.1998.2316. PMID 9878398.
Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.". Genome Res. 10 (10): 1546-60. PMID 11042152.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Ahn HC, Kim S, Lee BJ (2003). "Solution structure and p43 binding of the p38 leucine zipper motif: coiled-coil interactions mediate the association between p38 and p43.". FEBS Lett. 542 (1-3): 119-24. PMID 12729910.
Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805-11. doi:10.1038/nature02055. PMID 14574404.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Park BJ, Kang JW, Lee SW, et al. (2005). "The haploinsufficient tumor suppressor p18 upregulates p53 via interactions with ATM/ATR.". Cell 120 (2): 209-21. doi:10.1016/j.cell.2004.11.054. PMID 15680327.