EAF1

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ELL associated factor 1
Identifiers
Symbol(s) EAF1;
External IDs OMIM: 608315 MGI: 1921677 HomoloGene: 12561
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 85403 74427
Ensembl ENSG00000144597 ENSMUSG00000021890
Uniprot Q96JC9 Q9D4C5
Refseq NM_033083 (mRNA)
NP_149074 (protein)		 NM_028932 (mRNA)
NP_083208 (protein)
Location Chr 3: 15.44 - 15.46 Mb Chr 14: 30.32 - 30.34 Mb
Pubmed search [1] [2]

ELL associated factor 1, also known as EAF1, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: EAF1 ELL associated factor 1.

[edit] Further reading

  • Simone F, Polak PE, Kaberlein JJ, et al. (2001). "EAF1, a novel ELL-associated factor that is delocalized by expression of the MLL-ELL fusion protein.". Blood 98 (1): 201–9. PMID 11418481. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Polak PE, Simone F, Kaberlein JJ, et al. (2003). "ELL and EAF1 are Cajal body components that are disrupted in MLL-ELL leukemia.". Mol. Biol. Cell 14 (4): 1517–28. doi:10.1091/mbc.E02-07-0394. PMID 12686606. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Kong SE, Banks CA, Shilatifard A, et al. (2005). "ELL-associated factors 1 and 2 are positive regulators of RNA polymerase II elongation factor ELL.". Proc. Natl. Acad. Sci. U.S.A. 102 (29): 10094–8. doi:10.1073/pnas.0503017102. PMID 16006523. 
  • Xiao W, Jiang F, Wang Z (2006). "ELL binding regulates U19/Eaf2 intracellular localization, stability, and transactivation.". Prostate 66 (1): 1–12. doi:10.1002/pros.20309. PMID 16114057. 
  • Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. 
  • Jiang F, Ai J, Xiao W, Wang Z (2007). "FB1, an E2A fusion partner in childhood leukemia, interacts with U19/EAF2 and inhibits its transcriptional activity.". Cancer Lett. 253 (2): 265–72. doi:10.1016/j.canlet.2007.02.003. PMID 17395368. 
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