DYNLL2

From Wikipedia, the free encyclopedia

Dynein, light chain, LC8-type 2

PDB rendering based on 1cmi.

Available structures: 1cmi, 1f3c, 1f95, 1f96, 1pwj, 1pwk, 1re6, 1rhw, 2pg1

Identifiers

Symbol(s)

DYNLL2; DNCL1B; Dlc2; MGC17810

External IDs

OMIM: 608942 MGI: 1915347 HomoloGene: 2777

Gene ontology
Molecular Function:	• microtubule motor activity • protein binding
Cellular Component:	• microtubule • myosin complex • dynein complex
Biological Process:	• microtubule-based process • intracellular transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_080677 (mRNA)
NP_542408 (protein)

NM_026556 (mRNA)
NP_080832 (protein)

Location

Chr 17: 53.52 - 53.52 Mb

Chr 11: 87.8 - 87.8 Mb

Pubmed search

[1]

[2]

Dynein, light chain, LC8-type 2, also known as DYNLL2, is a human gene.^[1]

[edit] References

^ Entrez Gene: DYNLL2 dynein, light chain, LC8-type 2.

[edit] Further reading

Naisbitt S, Valtschanoff J, Allison DW, et al. (2000). "Interaction of the postsynaptic density-95/guanylate kinase domain-associated protein complex with a light chain of myosin-V and dynein.". J. Neurosci. 20 (12): 4524–34. PMID 10844022.
Haraguchi K, Satoh K, Yanai H, et al. (2001). "The hDLG-associated protein DAP interacts with dynein light chain and neuronal nitric oxide synthase.". Genes Cells 5 (11): 905–911. PMID 11122378.
Puthalakath H, Villunger A, O'Reilly LA, et al. (2001). "Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis.". Science 293 (5536): 1829–32. doi:10.1126/science.1062257. PMID 11546872.
Fuhrmann JC, Kins S, Rostaing P, et al. (2002). "Gephyrin interacts with Dynein light chains 1 and 2, components of motor protein complexes.". J. Neurosci. 22 (13): 5393–402. doi:20026552. PMID 12097491.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Day CL, Puthalakath H, Skea G, et al. (2004). "Localization of dynein light chains 1 and 2 and their pro-apoptotic ligands.". Biochem. J. 377 (Pt 3): 597–605. doi:10.1042/BJ20031251. PMID 14561217.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
Pfister KK, Fisher EM, Gibbons IR, et al. (2006). "Cytoplasmic dynein nomenclature.". J. Cell Biol. 171 (3): 411–3. doi:10.1083/jcb.200508078. PMID 16260502.