DTL (gene)

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Denticleless homolog (Drosophila)
Identifiers
Symbol(s) DTL; RAMP; CDT2; DCAF2; L2DTL
External IDs OMIM: 610617 MGI: 1924093 HomoloGene: 32313
Orthologs
Human Mouse
Entrez 51514 76843
Ensembl ENSG00000143476 ENSMUSG00000037474
Refseq NM_016448 (mRNA)
NP_057532 (protein)		 NM_029766 (mRNA)
NP_084042 (protein)
Location Chr 1: 210.28 - 210.34 Mb Chr 1: 193.24 - 193.28 Mb
Pubmed search [1] [2]

Denticleless homolog (Drosophila), also known as DTL, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: DTL denticleless homolog (Drosophila).

[edit] Further reading

  • Cheung WM, Chu AH, Chu PW, Ip NY (2001). "Cloning and expression of a novel nuclear matrix-associated protein that is regulated during the retinoic acid-induced neuronal differentiation.". J. Biol. Chem. 276 (20): 17083–91. doi:10.1074/jbc.M010802200. PMID 11278750. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414. 
  • Banks D, Wu M, Higa LA, et al. (2007). "L2DTL/CDT2 and PCNA interact with p53 and regulate p53 polyubiquitination and protein stability through MDM2 and CUL4A/DDB1 complexes.". Cell Cycle 5 (15): 1719–29. PMID 16861890. 
  • Higa LA, Banks D, Wu M, et al. (2007). "L2DTL/CDT2 interacts with the CUL4/DDB1 complex and PCNA and regulates CDT1 proteolysis in response to DNA damage.". Cell Cycle 5 (15): 1675–80. PMID 16861906. 
  • Jin J, Arias EE, Chen J, et al. (2006). "A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.". Mol. Cell 23 (5): 709–21. doi:10.1016/j.molcel.2006.08.010. PMID 16949367. 
  • Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. 
  • Higa LA, Wu M, Ye T, et al. (2006). "CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation.". Nat. Cell Biol. 8 (11): 1277–83. doi:10.1038/ncb1490. PMID 17041588. 
  • Sansam CL, Shepard JL, Lai K, et al. (2006). "DTL/CDT2 is essential for both CDT1 regulation and the early G2/M checkpoint.". Genes Dev. 20 (22): 3117–29. doi:10.1101/gad.1482106. PMID 17085480. 
  • Pan HW, Chou HY, Liu SH, et al. (2007). "Role of L2DTL, cell cycle-regulated nuclear and centrosome protein, in aggressive hepatocellular carcinoma.". Cell Cycle 5 (22): 2676–87. PMID 17106265. 
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