Talk:Dopamine receptor D4
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[edit] References
This article still needs some work. In particular, some chasing of the references mentioned at the end of the one WWW reference provided would probably be useful. I didn't cite any of the studies directly since I didn't read them. Should I have? Most of the rest of the stuff you can find on the WWW is a bit sensational and/or pertains to an article in Time Magazine...not the best place for genetics info. Jeeves 02:05, 9 Jun 2005 (UTC)
[edit] Elongated receptors response to dopamine
"cells with an elongated copy of this gene appear to react more strongly to dopamine molecules." Isn't it the other way around? In The Tangled Wing by Melvin Konnor (2002) New York NY: Henry Holt ISBN 0-7167-4602-6 p. 87 it says "Repeats make the protein longer, which makes the receptor weaker, so that it binds less dopamine." This quote from Konnor matches my understanding, which is that novelty-seeking or thrill-seeking is associated with less production of dopamine; fewer or weaker dopamine receptors; and faster breakdown of dopamine (though I might have some of that wrong), so that high stimulation is required in order to generate enough dopamine to have much of an effect. ☺ Coppertwig (talk) 13:38, 4 May 2008 (UTC)
