Domenico de Simone

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Domenico de Simone (29 November 1768 in Benevento in Italy - 9 November 1837 in Rome) was a cardinal of the Catholic Church. He was part of the Roman Curia.

He was made a cardinal in March 1830 by Pope Pius VIII.

He took part in the 1830–1831 conclave which chose Pope Gregory XVI.