DOCK7

From Wikipedia, the free encyclopedia

Dedicator of cytokinesis 7

Identifiers

DOCK7; KIAA1771; ZIR2

External IDs

MGI: 1914549 HomoloGene: 23566

Gene ontology
Molecular Function:	• guanyl-nucleotide exchange factor activity • GTP binding • GTPase binding
Biological Process:	• multicellular organismal development • nervous system development • cell differentiation

Orthologs

Human

Mouse

Refseq

NM_033407 (mRNA)
NP_212132 (protein)

NM_026082 (mRNA)
NP_080358 (protein)

Location

Chr 1: 62.69 - 62.93 Mb

Chr 4: 98.43 - 98.61 Mb

Pubmed search

[1]

[2]

Dedicator of cytokinesis 7, also known as DOCK7, is a human gene.^[1]

[edit] References

^ Entrez Gene: DOCK7 dedicator of cytokinesis 7.

[edit] Further reading

Nagase T, Kikuno R, Hattori A, et al. (2001). "Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.". DNA Res. 7 (6): 347-55. PMID 11214970.
Harrington JJ, Sherf B, Rundlett S, et al. (2001). "Creation of genome-wide protein expression libraries using random activation of gene expression.". Nat. Biotechnol. 19 (5): 440-5. doi:10.1038/88107. PMID 11329013.
Côté JF, Vuori K (2003). "Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.". J. Cell. Sci. 115 (Pt 24): 4901-13. PMID 12432077.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Brajenovic M, Joberty G, Küster B, et al. (2004). "Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network.". J. Biol. Chem. 279 (13): 12804-11. doi:10.1074/jbc.M312171200. PMID 14676191.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Jin J, Smith FD, Stark C, et al. (2004). "Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.". Curr. Biol. 14 (16): 1436-50. doi:10.1016/j.cub.2004.07.051. PMID 15324660.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Nellist M, Burgers PC, van den Ouweland AM, et al. (2005). "Phosphorylation and binding partner analysis of the TSC1-TSC2 complex.". Biochem. Biophys. Res. Commun. 333 (3): 818-26. doi:10.1016/j.bbrc.2005.05.175. PMID 15963462.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315-21. doi:10.1038/nature04727. PMID 16710414.
Watabe-Uchida M, John KA, Janas JA, et al. (2006). "The Rac activator DOCK7 regulates neuronal polarity through local phosphorylation of stathmin/Op18.". Neuron 51 (6): 727-39. doi:10.1016/j.neuron.2006.07.020. PMID 16982419.