DNAJC5

From Wikipedia, the free encyclopedia

DnaJ (Hsp40) homolog, subfamily C, member 5

PDB rendering based on 2ctw.

Available structures: 2ctw

Identifiers

Symbol(s)

DNAJC5; CSP; DKFZP434N1429; DKFZp761N1221; FLJ00118; FLJ13070

External IDs

MGI: 892995 HomoloGene: 9631

Gene ontology
Molecular Function:	• heat shock protein binding • unfolded protein binding
Cellular Component:	• membrane
Biological Process:	• protein folding

Orthologs

Human

Mouse

Refseq

NM_025219 (mRNA)
NP_079495 (protein)

XM_990872 (mRNA)
XP_995966 (protein)

Location

Chr 20: 62 - 62.04 Mb

Chr 2: 181.45 - 181.48 Mb

Pubmed search

[1]

[2]

DnaJ (Hsp40) homolog, subfamily C, member 5, also known as DNAJC5, is a human gene.^[1]

[edit] References

^ Entrez Gene: DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5.

[edit] Further reading

Coppola T, Gundersen C (1996). "Widespread expression of human cysteine string proteins.". FEBS Lett. 391 (3): 269-72. PMID 8764987.
Zhang H, Kelley WL, Chamberlain LH, et al. (1999). "Mutational analysis of cysteine-string protein function in insulin exocytosis.". J. Cell. Sci. 112 ( Pt 9): 1345-51. PMID 10194413.
Hattori A, Okumura K, Nagase T, et al. (2001). "Characterization of long cDNA clones from human adult spleen.". DNA Res. 7 (6): 357-66. PMID 11214971.
Evans GJ, Wilkinson MC, Graham ME, et al. (2002). "Phosphorylation of cysteine string protein by protein kinase A. Implications for the modulation of exocytosis.". J. Biol. Chem. 276 (51): 47877-85. doi:10.1074/jbc.M108186200. PMID 11604405.
Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20.". Nature 414 (6866): 865-71. doi:10.1038/414865a. PMID 11780052.
Zhang H, Peters KW, Sun F, et al. (2002). "Cysteine string protein interacts with and modulates the maturation of the cystic fibrosis transmembrane conductance regulator.". J. Biol. Chem. 277 (32): 28948-58. doi:10.1074/jbc.M111706200. PMID 12039948.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Miller LC, Swayne LA, Chen L, et al. (2004). "Cysteine string protein (CSP) inhibition of N-type calcium channels is blocked by mutant huntingtin.". J. Biol. Chem. 278 (52): 53072-81. doi:10.1074/jbc.M306230200. PMID 14570907.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Giorgianni F, Beranova-Giorgianni S, Desiderio DM (2004). "Identification and characterization of phosphorylated proteins in the human pituitary.". Proteomics 4 (3): 587-98. doi:10.1002/pmic.200300584. PMID 14997482.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Boal F, Zhang H, Tessier C, et al. (2005). "The variable C-terminus of cysteine string proteins modulates exocytosis and protein-protein interactions.". Biochemistry 43 (51): 16212-23. doi:10.1021/bi048612+. PMID 15610015.
Natochin M, Campbell TN, Barren B, et al. (2005). "Characterization of the G alpha(s) regulator cysteine string protein.". J. Biol. Chem. 280 (34): 30236-41. doi:10.1074/jbc.M500722200. PMID 15972823.
Zhang H, Schmidt BZ, Sun F, et al. (2006). "Cysteine string protein monitors late steps in cystic fibrosis transmembrane conductance regulator biogenesis.". J. Biol. Chem. 281 (16): 11312-21. doi:10.1074/jbc.M512013200. PMID 16469739.
Chi A, Valencia JC, Hu ZZ, et al. (2007). "Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.". J. Proteome Res. 5 (11): 3135-44. doi:10.1021/pr060363j. PMID 17081065.