DNAJB9

From Wikipedia, the free encyclopedia

DnaJ (Hsp40) homolog, subfamily B, member 9

PDB rendering based on 2ctr.

Available structures: 2ctr

Identifiers

Symbol(s)

DNAJB9; DKFZP564F1862; ERdj4; MDG1; MST049; MSTP049

External IDs

OMIM: 602634 MGI: 1351618 HomoloGene: 32155

Gene ontology
Molecular Function:	• chaperone regulator activity • heat shock protein binding • unfolded protein binding
Cellular Component:	• nucleus • nucleolus • cytoplasm • endoplasmic reticulum
Biological Process:	• protein folding

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_012328 (mRNA)
NP_036460 (protein)

NM_013760 (mRNA)
NP_038788 (protein)

Location

Chr 7: 108 - 108 Mb

n/a

Pubmed search

[1]

[2]

DnaJ (Hsp40) homolog, subfamily B, member 9, also known as DNAJB9, is a human gene.^[1]

[edit] References

^ Entrez Gene: DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9.

[edit] Further reading

Pröls F, Liehr T, Rinke R, Rautenstrauss B (1998). "Assignment of the microvascular endothelial differentiation gene 1 (MDG1) to human chromosome band 14q24.2-->q24.3 by fluorescence in situ hybridization.". Cytogenet. Cell Genet. 79 (1-2): 149-50. PMID 9533036.
Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.". Genome Res. 10 (10): 1546-60. PMID 11042152.
Ohtsuka K, Hata M (2001). "Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature.". Cell Stress Chaperones 5 (2): 98-112. PMID 11147971.
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.". Genome Res. 11 (3): 422-35. doi:10.1101/gr.154701. PMID 11230166.
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.". EMBO Rep. 1 (3): 287-92. doi:10.1093/embo-reports/kvd058. PMID 11256614.
Pröls F, Mayer MP, Renner O, et al. (2001). "Upregulation of the cochaperone Mdg1 in endothelial cells is induced by stress and during in vitro angiogenesis.". Exp. Cell Res. 269 (1): 42-53. doi:10.1006/excr.2001.5294. PMID 11525638.
Shen Y, Meunier L, Hendershot LM (2002). "Identification and characterization of a novel endoplasmic reticulum (ER) DnaJ homologue, which stimulates ATPase activity of BiP in vitro and is induced by ER stress.". J. Biol. Chem. 277 (18): 15947-56. doi:10.1074/jbc.M112214200. PMID 11836248.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Scherer SW, Cheung J, MacDonald JR, et al. (2003). "Human chromosome 7: DNA sequence and biology.". Science 300 (5620): 767-72. doi:10.1126/science.1083423. PMID 12690205.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265-70. doi:10.1101/gr.1293003. PMID 12975309.
Berger BJ, Müller TS, Buschmann IR, et al. (2003). "High levels of the molecular chaperone Mdg1/ERdj4 reflect the activation state of endothelial cells.". Exp. Cell Res. 290 (1): 82-92. PMID 14516790.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Lin KT, Lu RM, Tarn WY (2004). "The WW domain-containing proteins interact with the early spliceosome and participate in pre-mRNA splicing in vivo.". Mol. Cell. Biol. 24 (20): 9176-85. doi:10.1128/MCB.24.20.9176-9185.2004. PMID 15456888.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome.". Cell 122 (6): 957-68. doi:10.1016/j.cell.2005.08.029. PMID 16169070.