Dihydrostreptomycin-6-phosphate 3'alpha-kinase

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In enzymology, a dihydrostreptomycin-6-phosphate 3'alpha-kinase (EC 2.7.1.88) is an enzyme that catalyzes the chemical reaction

ATP + dihydrostreptomycin 6-phosphate ADP + dihydrostreptomycin 3'alpha,6-bisphosphate

Thus, the two substrates of this enzyme are ATP and dihydrostreptomycin 6-phosphate, whereas its two products are ADP and dihydrostreptomycin 3'alpha,6-bisphosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:dihydrostreptomycin-6-phosphate 3'alpha-phosphotransferase. Other names in common use include dihydrostreptomycin 6-phosphate kinase (phosphorylating), and ATP:dihydrostreptomycin-6-P 3'alpha-phosphotransferase.

[edit] References

• IUBMB entry for 2.7.1.88
• BRENDA references for 2.7.1.88 (Recommended.)
• PubMed references for 2.7.1.88
• PubMed Central references for 2.7.1.88
• Google Scholar references for 2.7.1.88
• Walker JB, Skorvaga M (1973). "Phosphorylation of streptomycin and dihydrostreptomycin by Streptomyces. Enzymatic synthesis of different diphosphorylated derivatives". J. Biol. Chem. 248: 2435–40. PMID 4121456. 

[edit] External links

The CAS registry number for this enzyme class is 39391-14-5.

• IUBMB entry for 2.7.1.88

• KEGG entry for 2.7.1.88

• BRENDA entry for 2.7.1.88

• NiceZyme view of 2.7.1.88

• EC2PDB: PDB structures for 2.7.1.88

• PRIAM entry for 2.7.1.88

• PUMA2 entry for 2.7.1.88

• IntEnz: Integrated Enzyme entry for 2.7.1.88

• MetaCyc entry for 2.7.1.88

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047333: dihydrostreptomycin-6-phosphate 3'-alpha-kinase

• AMIGO entry for GO code 0047333: dihydrostreptomycin-6-phosphate 3'-alpha-kinase