Diglucosyl diacylglycerol synthase
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In enzymology, a diglucosyl diacylglycerol synthase (EC 2.4.1.208) is an enzyme that catalyzes the chemical reaction
- UDP-glucose + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol
1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1->2)-O-alpha-D- glucopyranosyl)sn-glycerol + UDP
Thus, the two substrates of this enzyme are UDP-glucose and 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol, whereas its 3 products are [[1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1->2)-O-alpha-D-]], glucopyranosyl)sn-glycerol, and UDP.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol (1->2) glucosyltransferase. Other names in common use include monoglucosyl diacylglycerol (1->2) glucosyltransferase, MGlcDAG (1->2) glucosyltransferase, and DGlcDAG synthase. It employs one cofactor, magnesium.
[edit] References
- IUBMB entry for 2.4.1.208
- BRENDA references for 2.4.1.208 (Recommended.)
- PubMed references for 2.4.1.208
- PubMed Central references for 2.4.1.208
- Google Scholar references for 2.4.1.208
- Karlsson OP, Rytomaa M, Dahlqvist A, Kinnunen PK, Wieslander A (1996). "Correlation between bilayer lipid dynamics and activity of the diglucosyldiacylglycerol synthase from Acholeplasma laidlawii membranes". Biochemistry. 35: 10094–102. doi:. PMID 8756472.
[edit] External links
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- The CAS registry number for this enzyme class is 168680-19-1.
[edit] Gene Ontology (GO) codes
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