Diaminobutyrate-pyruvate transaminase

From Wikipedia, the free encyclopedia

In enzymology, a diaminobutyrate-pyruvate transaminase (EC 2.6.1.46) is an enzyme that catalyzes the chemical reaction

L-2,4-diaminobutanoate + pyruvate L-aspartate 4-semialdehyde + L-alanine

Thus, the two substrates of this enzyme are L-2,4-diaminobutanoate and pyruvate, whereas its two products are L-aspartate 4-semialdehyde and L-alanine.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is L-2,4-diaminobutanoate:pyruvate aminotransferase. Other names in common use include diaminobutyrate-pyruvate aminotransferase, and L-diaminobutyric acid transaminase. It employs one cofactor, pyridoxal phosphate.

[edit] References

• IUBMB entry for 2.6.1.46
• BRENDA references for 2.6.1.46 (Recommended.)
• PubMed references for 2.6.1.46
• PubMed Central references for 2.6.1.46
• Google Scholar references for 2.6.1.46
• Rao DR, Hariharan K, Vijayalakshmi KR (1969). "A study of the metabolism of L-alpha gamma-diaminobutyric acid in a Xanthomonas species". Biochem. J. 114: 107–15. PMID 4390206. 

[edit] External links

The CAS registry number for this enzyme class is 37277-95-5.

• IUBMB entry for 2.6.1.46

• KEGG entry for 2.6.1.46

• BRENDA entry for 2.6.1.46

• NiceZyme view of 2.6.1.46

• EC2PDB: PDB structures for 2.6.1.46

• PRIAM entry for 2.6.1.46

• PUMA2 entry for 2.6.1.46

• IntEnz: Integrated Enzyme entry for 2.6.1.46

• MetaCyc entry for 2.6.1.46

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047307: diaminobutyrate-pyruvate transaminase

• AMIGO entry for GO code 0047307: diaminobutyrate-pyruvate transaminase