DERL3 (gene)

From Wikipedia, the free encyclopedia

Der1-like domain family, member 3

Identifiers

DERL3; C22orf14; IZP6; MGC71803

External IDs

OMIM: 610305 MGI: 1917627 HomoloGene: 41566

Gene ontology
Molecular Function:	• protein binding
Cellular Component:	• endoplasmic reticulum • membrane • integral to membrane • integral to endoplasmic reticulum membrane
Biological Process:	• ER-associated protein catabolic process • unfolded protein response

Orthologs

Human

Mouse

Refseq

NM_001002862 (mRNA)
NP_001002862 (protein)

NM_024440 (mRNA)
NP_077760 (protein)

Location

Chr 22: 22.51 - 22.51 Mb

Chr 10: 75.34 - 75.34 Mb

Pubmed search

[1]

[2]

Der1-like domain family, member 3, also known as DERL3, is a human gene.^[1]

[edit] References

^ Entrez Gene: DERL3 Der1-like domain family, member 3.

[edit] Further reading

Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791-806. PMID 8889548.
Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22.". Nature 402 (6761): 489-95. doi:10.1038/990031. PMID 10591208.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Lilley BN, Ploegh HL (2004). "A membrane protein required for dislocation of misfolded proteins from the ER.". Nature 429 (6994): 834-40. doi:10.1038/nature02592. PMID 15215855.
Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome.". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMID 15461802.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Oda Y, Okada T, Yoshida H, et al. (2006). "Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation.". J. Cell Biol. 172 (3): 383-93. doi:10.1083/jcb.200507057. PMID 16449189.
Wang X, Bolotin D, Chu DH, et al. (2006). "AP-2alpha: a regulator of EGF receptor signaling and proliferation in skin epidermis.". J. Cell Biol. 172 (3): 409-21. doi:10.1083/jcb.200510002. PMID 16449191.
Morrison JI, Lööf S, He P, Simon A (2006). "Salamander limb regeneration involves the activation of a multipotent skeletal muscle satellite cell population.". J. Cell Biol. 172 (3): 433-40. doi:10.1083/jcb.200509011. PMID 16449193.