DCPS (gene)

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Decapping enzyme, scavenger
PDB rendering based on 1st0.
Available structures: 1st0, 1st4, 1xml, 1xmm
Identifiers
Symbol(s) DCPS; HINT-5; HSL1; HSPC015
External IDs OMIM: 610534 MGI: 1916555 HomoloGene: 32202
Orthologs
Human Mouse
Entrez 28960 69305
Ensembl ENSG00000110063 ENSMUSG00000032040
Uniprot Q96C86 Q9DAR7
Refseq NM_014026 (mRNA)
NP_054745 (protein)		 NM_027030 (mRNA)
NP_081306 (protein)
Location Chr 11: 125.68 - 125.72 Mb Chr 9: 34.87 - 34.93 Mb
Pubmed search [1] [2]

Decapping enzyme, scavenger, also known as DCPS, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: DCPS decapping enzyme, scavenger.

[edit] Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149. 
  • Zhang QH, Ye M, Wu XY, et al. (2001). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells.". Genome Res. 10 (10): 1546–60. PMID 11042152. 
  • Wang Z, Kiledjian M (2002). "Functional link between the mammalian exosome and mRNA decapping.". Cell 107 (6): 751–62. PMID 11747811. 
  • Liu H, Rodgers ND, Jiao X, Kiledjian M (2002). "The scavenger mRNA decapping enzyme DcpS is a member of the HIT family of pyrophosphatases.". EMBO J. 21 (17): 4699–708. PMID 12198172. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Kwasnicka DA, Krakowiak A, Thacker C, et al. (2003). "Coordinate expression of NADPH-dependent flavin reductase, Fre-1, and Hint-related 7meGMP-directed hydrolase, DCS-1.". J. Biol. Chem. 278 (40): 39051–8. doi:10.1074/jbc.M306355200. PMID 12871939. 
  • van Dijk E, Le Hir H, Séraphin B (2003). "DcpS can act in the 5'-3' mRNA decay pathway in addition to the 3'-5' pathway.". Proc. Natl. Acad. Sci. U.S.A. 100 (21): 12081–6. doi:10.1073/pnas.1635192100. PMID 14523240. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Gu M, Fabrega C, Liu SW, et al. (2004). "Insights into the structure, mechanism, and regulation of scavenger mRNA decapping activity.". Mol. Cell 14 (1): 67–80. PMID 15068804. 
  • Liu SW, Jiao X, Liu H, et al. (2004). "Functional analysis of mRNA scavenger decapping enzymes.". RNA 10 (9): 1412–22. doi:10.1261/rna.7660804. PMID 15273322. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Chen N, Walsh MA, Liu Y, et al. (2005). "Crystal structures of human DcpS in ligand-free and m7GDP-bound forms suggest a dynamic mechanism for scavenger mRNA decapping.". J. Mol. Biol. 347 (4): 707–18. doi:10.1016/j.jmb.2005.01.062. PMID 15769464. 
  • Kwaśnicka-Crawford DA, Vincent SR (2005). "Role of a novel dual flavin reductase (NR1) and an associated histidine triad protein (DCS-1) in menadione-induced cytotoxicity.". Biochem. Biophys. Res. Commun. 336 (2): 565–71. doi:10.1016/j.bbrc.2005.08.129. PMID 16140270. 
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