DCP1B

From Wikipedia, the free encyclopedia

DCP1 decapping enzyme homolog B (S. cerevisiae)

Identifiers

DCP1B; DCP1; hDcp1b

External IDs

OMIM: 609843 MGI: 2442404 HomoloGene: 51881

Gene ontology
Molecular Function:	• hydrolase activity
Cellular Component:	• nucleus
Biological Process:	• mRNA catabolic process, nonsense-mediated decay

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

n/a

Refseq

NM_152640 (mRNA)
NP_689853 (protein)

XM_977605 (mRNA)
XP_982699 (protein)

Location

Chr 12: 1.93 - 1.98 Mb

Chr 6: 119.14 - 119.19 Mb

Pubmed search

[1]

[2]

DCP1 decapping enzyme homolog B (S. cerevisiae), also known as DCP1B, is a human gene.^[1]

DCP1B is a core component of the mRNA decapping complex, a key factor in the regulation of mRNA decay (Lykke-Andersen, 2002).[supplied by OMIM]^[1]

[edit] References

^ ^a ^b Entrez Gene: DCP1B DCP1 decapping enzyme homolog B (S. cerevisiae).

[edit] Further reading

Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
Rush J, Moritz A, Lee KA, et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.". Nat. Biotechnol. 23 (1): 94–101. doi:10.1038/nbt1046. PMID 15592455.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Lehner B, Sanderson CM (2004). "A protein interaction framework for human mRNA degradation.". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMID 15231747.
Cougot N, Babajko S, Séraphin B (2004). "Cytoplasmic foci are sites of mRNA decay in human cells.". J. Cell Biol. 165 (1): 31–40. doi:10.1083/jcb.200309008. PMID 15067023.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Lykke-Andersen J (2003). "Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay.". Mol. Cell. Biol. 22 (23): 8114–21. PMID 12417715.