DCLRE1B

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DNA cross-link repair 1B (PSO2 homolog, S. cerevisiae)
Identifiers
Symbol(s) DCLRE1B; DKFZp686C24187; FLJ12810; FLJ13998; SNM1B
External IDs OMIM: 609683 MGI: 2156057 HomoloGene: 32553
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 64858 140917
Ensembl ENSG00000118655 ENSMUSG00000027845
Uniprot Q9H816 A0JLW2
Refseq NM_022836 (mRNA)
NP_073747 (protein)		 NM_001025312 (mRNA)
NP_001020483 (protein)
Location Chr 1: 114.25 - 114.26 Mb Chr 3: 103.93 - 103.94 Mb
Pubmed search [1] [2]

DNA cross-link repair 1B (PSO2 homolog, S. cerevisiae), also known as DCLRE1B, is a human gene.[1]

DNA interstrand cross-links prevent strand separation, thereby physically blocking transcription, replication, and segregation of DNA. DCLRE1B is one of several evolutionarily conserved genes involved in repair of interstrand cross-links (Dronkert et al., 2000).[supplied by OMIM][1]

[edit] References

  1. ^ a b Entrez Gene: DCLRE1B DNA cross-link repair 1B (PSO2 homolog, S. cerevisiae).

[edit] Further reading

  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Demuth I, Digweed M, Concannon P (2004). "Human SNM1B is required for normal cellular response to both DNA interstrand crosslink-inducing agents and ionizing radiation.". Oncogene 23 (53): 8611-8. doi:10.1038/sj.onc.1207895. PMID 15467758. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Ishiai M, Kimura M, Namikoshi K, et al. (2004). "DNA cross-link repair protein SNM1A interacts with PIAS1 in nuclear focus formation.". Mol. Cell. Biol. 24 (24): 10733-41. doi:10.1128/MCB.24.24.10733-10741.2004. PMID 15572677. 
  • Freibaum BD, Counter CM (2006). "hSnm1B is a novel telomere-associated protein.". J. Biol. Chem. 281 (22): 15033-6. doi:10.1074/jbc.C600038200. PMID 16606622. 
  • Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1.". Nature 441 (7091): 315-21. doi:10.1038/nature04727. PMID 16710414. 
  • Lenain C, Bauwens S, Amiard S, et al. (2006). "The Apollo 5' exonuclease functions together with TRF2 to protect telomeres from DNA repair.". Curr. Biol. 16 (13): 1303-10. doi:10.1016/j.cub.2006.05.021. PMID 16730175. 
  • van Overbeek M, de Lange T (2006). "Apollo, an Artemis-related nuclease, interacts with TRF2 and protects human telomeres in S phase.". Curr. Biol. 16 (13): 1295-302. doi:10.1016/j.cub.2006.05.022. PMID 16730176. 
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