D-glutamyltransferase

From Wikipedia, the free encyclopedia

In enzymology, a D-glutamyltransferase (EC 2.3.2.1) is an enzyme that catalyzes the chemical reaction

L(or D)-glutamine + D-glutamyl-peptide NH₃ + 5-glutamyl-D-glutamyl-peptide

The 3 substrates of this enzyme are L-glutamine, D-glutamine, and D-glutamyl-peptide, whereas its two products are NH₃ and 5-glutamyl-D-glutamyl-peptide.

This enzyme belongs to the family of transferases, specifically the aminoacyltransferases. The systematic name of this enzyme class is glutamine:D-glutamyl-peptide 5-glutamyltransferase. Other names in common use include D-glutamyl transpeptidase, and D-gamma-glutamyl transpeptidase. This enzyme participates in d-glutamine and d-glutamate metabolism.

[edit] References

• IUBMB entry for 2.3.2.1
• BRENDA references for 2.3.2.1 (Recommended.)
• PubMed references for 2.3.2.1
• PubMed Central references for 2.3.2.1
• Google Scholar references for 2.3.2.1
• Williams WJ, Litwin J and Thorne CB (1955). "Further studies on the biosynthesis of gamma-glutamyl peptides by transfer reactions". J. Biol. Chem. 212: 427–438. 

[edit] External links

The CAS registry number for this enzyme class is 9030-02-8.

• IUBMB entry for 2.3.2.1

• KEGG entry for 2.3.2.1

• BRENDA entry for 2.3.2.1

• NiceZyme view of 2.3.2.1

• EC2PDB: PDB structures for 2.3.2.1

• PRIAM entry for 2.3.2.1

• PUMA2 entry for 2.3.2.1

• IntEnz: Integrated Enzyme entry for 2.3.2.1

• MetaCyc entry for 2.3.2.1

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047823: D-glutamyltransferase

• AMIGO entry for GO code 0047823: D-glutamyltransferase