D-glutamate(D-aspartate) oxidase

From Wikipedia, the free encyclopedia

In enzymology, a D-glutamate(D-aspartate) oxidase (EC 1.4.3.15) is an enzyme that catalyzes the chemical reaction

D-glutamate + H₂O + O₂ 2-oxoglutarate + NH₃ + H₂O₂

The 3 substrates of this enzyme are D-glutamate, H₂O, and O₂, whereas its 3 products are 2-oxoglutarate, NH₃, and H₂O₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with oxygen as acceptor. The systematic name of this enzyme class is D-glutamate(D-aspartate):oxygen oxidoreductase (deaminating). Other names in common use include D-glutamic-aspartic oxidase, and D-monoaminodicarboxylic acid oxidase. This enzyme participates in alanine and aspartate metabolism. It employs one cofactor, FAD.

[edit] References

• IUBMB entry for 1.4.3.15
• BRENDA references for 1.4.3.15 (Recommended.)
• PubMed references for 1.4.3.15
• PubMed Central references for 1.4.3.15
• Google Scholar references for 1.4.3.15
• Mizushima S (1957). "Purified D-glutamic-aspartic oxidase of Aspergillus ustus". J. Gen. Appl. Microbiol. 3: 233–239. 

[edit] External links

• IUBMB entry for 1.4.3.15

• KEGG entry for 1.4.3.15

• BRENDA entry for 1.4.3.15

• NiceZyme view of 1.4.3.15

• EC2PDB: PDB structures for 1.4.3.15

• PRIAM entry for 1.4.3.15

• PUMA2 entry for 1.4.3.15

• IntEnz: Integrated Enzyme entry for 1.4.3.15

• MetaCyc entry for 1.4.3.15

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047819: D-glutamate(D-aspartate) oxidase

• AMIGO entry for GO code 0047819: D-glutamate(D-aspartate) oxidase