Cytochalasin E

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Cytochalasin E, a member of the Cytochalasin group, is an inhibitor of actin polymerization in blood platelets. It inhibits angiogenesis and tumor growth. Unlike cytochalasin A and cytochalasin B, it does not inhibit glucose transport.

Because of its antiangiogenic effect, Cytochalasin E is mentioned as a potential drug for age-related macular degeneration, a kind of blindness caused by an abnormal proliferation of blood vessels in the eye.^[1]