Cysteine lyase

From Wikipedia, the free encyclopedia

In enzymology, a cysteine lyase (EC 4.4.1.10) is an enzyme that catalyzes the chemical reaction

L-cysteine + sulfite L-cysteate + hydrogen sulfide

Thus, the two substrates of this enzyme are L-cysteine and sulfite, whereas its two products are L-cysteate and hydrogen sulfide.

This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The systematic name of this enzyme class is L-cysteine hydrogen-sulfide-lyase (adding sulfite L-cysteate-forming). Other names in common use include cysteine (sulfite) lyase, and L-cysteine hydrogen-sulfide-lyase (adding sulfite). This enzyme participates in cysteine metabolism and taurine and hypotaurine metabolism. It employs one cofactor, pyridoxal phosphate.

[edit] References

• IUBMB entry for 4.4.1.10
• BRENDA references for 4.4.1.10 (Recommended.)
• PubMed references for 4.4.1.10
• PubMed Central references for 4.4.1.10
• Google Scholar references for 4.4.1.10
• Tolosa EA, Chepurnova NK, Khomutov RM, Severin ES (1969). "Reactions catalysed by cysteine lyase from the yolk sac of chicken embryo". Biochim. Biophys. Acta. 171: 369–71. PMID 5813025. 

[edit] External links

The CAS registry number for this enzyme class is 9079-86-1.

• IUBMB entry for 4.4.1.10

• KEGG entry for 4.4.1.10

• BRENDA entry for 4.4.1.10

• NiceZyme view of 4.4.1.10

• EC2PDB: PDB structures for 4.4.1.10

• PRIAM entry for 4.4.1.10

• PUMA2 entry for 4.4.1.10

• IntEnz: Integrated Enzyme entry for 4.4.1.10

• MetaCyc entry for 4.4.1.10

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047803: cysteine lyase

• AMIGO entry for GO code 0047803: cysteine lyase