Cysteine-S-conjugate N-acetyltransferase

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In enzymology, a cysteine-S-conjugate N-acetyltransferase (EC 2.3.1.80) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + an S-substituted L-cysteine CoA + an S-substituted N-acetyl-L-cysteine

Thus, the two substrates of this enzyme are acetyl-CoA and S-substituted L-cysteine, whereas its two products are CoA and S-substituted N-acetyl-L-cysteine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:S-substituted L-cysteine N-acetyltransferase. This enzyme participates in glutathione metabolism.

[edit] References

• IUBMB entry for 2.3.1.80
• BRENDA references for 2.3.1.80 (Recommended.)
• PubMed references for 2.3.1.80
• PubMed Central references for 2.3.1.80
• Google Scholar references for 2.3.1.80
• Duffel MW, Jakoby WB (1982). "Cysteine S-conjugate N-acetyltransferase from rat kidney microsomes". Mol. Pharmacol. 21: 444–8. PMID 6892478. 

[edit] External links

The CAS registry number for this enzyme class is 81725-80-6.

• IUBMB entry for 2.3.1.80

• KEGG entry for 2.3.1.80

• BRENDA entry for 2.3.1.80

• NiceZyme view of 2.3.1.80

• EC2PDB: PDB structures for 2.3.1.80

• PRIAM entry for 2.3.1.80

• PUMA2 entry for 2.3.1.80

• IntEnz: Integrated Enzyme entry for 2.3.1.80

• MetaCyc entry for 2.3.1.80

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047198: cysteine-S-conjugate N-acetyltransferase

• AMIGO entry for GO code 0047198: cysteine-S-conjugate N-acetyltransferase