Cypridina-luciferin 2-monooxygenase

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In enzymology, a Cypridina-luciferin 2-monooxygenase (EC 1.13.12.6) is an enzyme that catalyzes the chemical reaction

Cypridina luciferin + O₂ $\rightleftharpoons$ oxidized Cypridina luciferin + CO₂ + hnu

Thus, the two substrates of this enzyme are Cypridina luciferin and O₂, whereas its 3 products are oxidized Cypridina luciferin, CO₂, and hn.

This enzyme belongs to the family of oxidoreductases, specifically those acting on single donors with O₂ as oxidant and incorporation of two atoms of oxygen into the substrate (oxygenases). The oxygen incorporated need not be derived from O with incorporation of one atom of oxygen (internal monooxygenases o internal mixed-function oxidases). The systematic name of this enzyme class is Cypridina-luciferin:oxygen 2-oxidoreductase (decarboxylating). Other names in common use include Cypridina-type luciferase, luciferase (Cypridina luciferin), and Cypridina luciferase.

[edit] References

IUBMB entry for 1.13.12.6
BRENDA references for 1.13.12.6 (Recommended.)
PubMed references for 1.13.12.6
PubMed Central references for 1.13.12.6
Google Scholar references for 1.13.12.6
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Karpetsky TP and White EH (1973). "The synthesis of Cypridina etioluciferamine and the proof of the structure of Cypridina luciferin". Tetrahedron 29: 3761–3773. doi:10.1016/0040-4020(73)80193-0.
Kishi Y, Goto, T, Hirata Y, Shiromura O and Johnson FH (1966). "Cypridina bioluminescence. I. Structure of Cypridina luciferin". Tetrahedron Lett.: 3427–3436.
Tsuji FI, Lynch RV 3rd Stevens CL (1974). "Some properties of luciferase from the bioluminescent crustacean, Cypridina hilgendorfii". Biochemistry. 13: 5204–9. doi:10.1021/bi00722a024. PMID 4433517.