CTNNAL1

From Wikipedia, the free encyclopedia

Catenin (cadherin-associated protein), alpha-like 1

Identifiers

CTNNAL1; CLLP; alpha-CATU

External IDs

OMIM: 604785 MGI: 1859649 HomoloGene: 2815

Gene ontology
Molecular Function:	• structural molecule activity • cadherin binding
Cellular Component:	• actin cytoskeleton
Biological Process:	• apoptosis • cell adhesion

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_003798 (mRNA)
NP_003789 (protein)

XM_980596 (mRNA)
XP_985690 (protein)

Location

Chr 9: 110.74 - 110.82 Mb

Chr 4: 56.9 - 56.96 Mb

Pubmed search

[1]

[2]

Catenin (cadherin-associated protein), alpha-like 1, also known as CTNNAL1, is a human gene.^[1]

[edit] References

^ Entrez Gene: CTNNAL1 catenin (cadherin-associated protein), alpha-like 1.

[edit] Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Zhang JS, Nelson M, Wang L, et al. (1999). "Identification and chromosomal localization of CTNNAL1, a novel protein homologous to alpha-catenin.". Genomics 54 (1): 149–54. doi:10.1006/geno.1998.5458. PMID 9806841.
Janssens B, Staes K, van Roy F (1999). "Human alpha-catulin, a novel alpha-catenin-like molecule with conserved genomic structure, but deviating alternative splicing.". Biochim. Biophys. Acta 1447 (2-3): 341–7. PMID 10542337.
Demacio PC, Ray PN (2002). "Alpha-catulin maps to the familial dysautonomia region on 9q31.". Genome 44 (6): 990–4. PMID 11768226.
Park B, Nguyen NT, Dutt P, et al. (2003). "Association of Lbc Rho guanine nucleotide exchange factor with alpha-catenin-related protein, alpha-catulin/CTNNAL1, supports serum response factor activation.". J. Biol. Chem. 277 (47): 45361–70. doi:10.1074/jbc.M202447200. PMID 12270917.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Shieh YS, Chang LC, Chiu KC, et al. (2003). "Cadherin and catenin expression in mucoepidermoid carcinoma: correlation with histopathologic grade, clinical stage, and patient outcome.". J. Oral Pathol. Med. 32 (5): 297–304. PMID 12694354.
Surpili MJ, Delben TM, Kobarg J (2004). "Identification of proteins that interact with the central coiled-coil region of the human protein kinase NEK1.". Biochemistry 42 (51): 15369–76. doi:10.1021/bi034575v. PMID 14690447.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Merdek KD, Nguyen NT, Toksoz D (2004). "Distinct activities of the alpha-catenin family, alpha-catulin and alpha-catenin, on beta-catenin-mediated signaling.". Mol. Cell. Biol. 24 (6): 2410–22. PMID 14993280.
Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9.". Nature 429 (6990): 369–74. doi:10.1038/nature02465. PMID 15164053.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.